RIT/PROLO & PROLOZONE®

DEFINED

INJECTION

MEDICATIONS

LIST OF

PAINFUL

CONDITIONS

RIT/PROLO

TREATS

Nutrition

DELIVERY

FROM RIT/PROLO

PREVIOUS

QUESTIONS

WITH ANSWERS

AVERAGE NUMBER

OF TREATMENTS

AND TIME

TYPES OF JOINTS

DEFINITION OF RIT/PROLOTHERAPY & PROLOZONE®

                                                       Regenerative Injection Therapy/(RIT)

Is also known as prolotherapy or sclerotherapy is an interventional pain management technique that repetitively provides a mild neurolytic effect followed by a complex restorative process with biochemically induced collagen regeneration.

It is also called Reconstructive Therapy, It is a non-surgical ligament reconstruction that accelerates the rate of cartilage growth. This therapy is effective because it addresses and eliminates the

cause of chronic pain arising from connective tissue such as ligaments, tendons and cartilage.

It is an injection technique that has been shown to cause growth of cells and tissue to stabilize

and strengthen weakened joints, cartilage, ligaments and tendons. It rebuilds and strengthens

the complete joint structure even in patients with no cartilage. This therapy may eliminate the

need for joint replacement which usually takes three or more months to recover and

costs thousands. Some  family doctors prescribe pain killers, NSAIDs and Cortisone shots which

offer only temporary relief.

The term prolotherapy is derived from the word prolo, short for proliferation, as the therapy

is intended to proliferate tissue growth in the damaged area. This is also called Regenerative

Injection Therapy (RIT), since it is recognized that it extends beyond  the proliferative

stage-now understood as only the second stage of regenerative healing process.

The idea behind this therapy dates back more than 2000 years to Hippocrates, who used it to

treat soldiers with injured shoulders. Instead of injections Hippocrates used a hot poker, which

he speared into the shoulder joint, causing and stimulating the body to repair itself

of inflammation.

The injection is placed into the damaged ligament or tendon at the point where it attaches to

the bone. The injection produces an inflammation, which increases blood flow, swelling, and

pain. The body then launches a course of repair and healing.

1. The inflammation tricks the body into thinking another injury has occurred, so it sends

    in macrophages, which are cells that ingest and destroy the irritant solution. These cells

    clean up the area.

2. The body then sends in fibroblasts, which are cells that help build fibrous tissue. The

    fibroblasts excrete collagen, a protein that makes the ligaments denser and stronger.

   The  stronger ligaments provide more support for the joints and alleviates  the pain.

The new Prolotherapy by Dr. Robert Jay Rowen. (March 2009)

Prolotherapy has gone to a new and better level of pain relief and joint repair. This is a modification of Prolotherapy that provides outstanding proven results based on case studies.  The new technique was developed by Dr. Frank Shallenberger and is called:

                                                                                   PROLOZONE®

                                      Go to Dr. Shallenberger's website on the Links Page.

This procedure uses an oxygen/ozone gas mixture which directs oxidation to the affected painful area.  The affected area is anesthetized with procaine, a local anesthetic, vitamin B12 and folic acid is added to the procaine.  This combination stimulates the DNA of cells to start repairs to the damaged joint and relieves pain at once. Oxygen/ozone is the most critical nutrient for energy production and healing and is the magic ingredient in the new prolotherapy.

Dr. Robert Jay Rowan said the meniscus doesn't repair itself because cartilage does not have a

blood supply. It receives is oxygen and nutrients from the synovial fluid that baths the joints.

Nutrition must migrate in through osmosis. Very good results have been obtained by injection

ozone directly into the joint.

Ozone is a very active form of oxygen and it  stimulates cartilage growth and can stimulate damaged

articular cartilage back to reasonable function. The meniscus is a piece of cartilage between the

femur and tibia, not on the bone  surface.

Another approach is growth hormone which also stimulates cartilage growth.  Combine Ozone,

growth hormone and prolotherapy for joint problems have had  wonderful results according to my

colleagues.

"According to reports I have received, prolotherapy/ PROLOZONE®. has  helped joint mechanics

                                               almost no matter the underlying problem".

The ligaments and tendons produced after RIT/Prolotherapy appear much the same as normal tissue, except that they are thicker, stronger, and contain fibers of varying thickness, testifying to the new and on going creation of tissue which stimulates the natural healing process.

The injections stimulate blood vessel growth into tissues. This increases oxygen, nutrients

and growth factor delivery to the areas in the joint structure which facilitates healing.

In a double blind human study, in which neither the patients nor the researchers knew who were receiving the treatment, 88.5% of those injected with the reconstructive solution (RIT/Prolotherapy) showed improvement and the other study group showed

 0% improvement. It is a very conservative treatment and doesn't remove or replace parts or weakened areas of the body. There are no side effects such as possible blood clots or infection that sometimes occur with joint replacements. There is no downtime, usually the injections are done in the late afternoon and you can return to work or play the next day.

                                                                   (Source : from the internet)

The Prolotherapy injection consist of the following medications

The following medications may be used as a single solution or in different combinations:

Dextrose, utilized in intravenous solutions, when injected into the ligament, produces a temporary

inflammatory response, causing specialized cells called fibroblasts to migrate to the injected site 

and produce new collagen (the protein found in ligaments).

Phenol, used in many inject able medications as a preservative to prevent the growth of bacteria,

also induces the growth of new collagen in connective tissue, and has some properties as a

long-lasting local anesthetic. Xylocaine, Marcaine and Lidocaine are local anesthetics.

Sodium morrhuate (a derivative of cod liver oil) stimulates collagen formation.

The PROLOZONE® injection consist of the following medications

Oxygen/ozone gas mixture instead of the prolo solution. The affected joint is anesthetized with procaine which is a local anesthetic.

B12 and folic acid is added to the procaine and this combination will stimulate the DNA of cells to jump into repair action faster and longer than other treatments.

Oxygen called ozone is the most critical nutrient for energy production and healing. It stimulates the cells to excrete waste material and promotes their ability to repair themselves and the tissues around them.

This makes PROLOZONE® a miracle healer as ozone is a powerful stimulant of

cellular growth factors such as Transforming Growth Factor Beta (TGF-B).

The full report can be found in Dr. Robert Jay Rowen's Second Opinion Newsletter March 2009 Vol. XIX NO 3.

              Dr. Frank Shallenberger's website can be found on the LINKS PAGE.